Gardner Center for Parkinson's Disease

and Movement Disorders

234 Goodman Street, Cincinnati, Ohio 45219 | (866) 941-UCNI (8264)

Effect of low versus high frequency subthalamic nucleus deep brain stimulation on freezing of gait in patients with Parkinson’s disease

Study Number: 
Investigator Initiated
Topic: 
Parkinson's Disease - DBS - freezing of gait
Pricipal Investigator: 
Andrew P Duker
Ongoing: 
Ongoing
Place: 
Medical Arts Building
Overview: 

Specific Aims for this Pilot Study: 1) To determine the extent to which lowering the frequency of subthalamic nucleus deep brain stimulation (STN DBS) can improve freezing of gait in patients with idiopathic Parkinson’s disease, as measured by specific gait parameters of velocity, stride length, and cadence on a validated gait analysis system and 2) To further explore the potential mechanisms for this improvement by correlating positive or negative results to the localization of the active DBS electrode contact

Qualifications: 

Subjects ranging from 35 to 95 years of age who have idiopathic Parkinson’s disease, have freezing of gait as a symptom, and have undergone STN DBS for PD. These patients will be stabilized on their current programming parameters and should be at least six months out from initial programming.

Contact: 

For more information, please contact Megan Payne, MS at megan.payne@uc.edu or (513) 558-4759.