and Movement Disorders
234 Goodman Street, Cincinnati, Ohio 45219 | (866) 941-UCNI (8264)
234 Goodman Street, Cincinnati, Ohio 45219 | (866) 941-UCNI (8264)
The primary objective will be to compare subjects treated with CoQ10 (2400 mg/day) with those treated with matching placebo with regard to the change in total functional capacity, a measure of functional disability, between baseline and the Month 60 visit. The TFC is a valid and reliable measure of disease progression and is particularly responsive to change in early and mid-stages of HD, which will be the focus of this trial.
Subjects must have clinical features of HD and a confirmatory family history of HD, OR a CAG repeat expansion ≥ 36. Subject’s TFC > 9, must be ambulatory and not require skilled nursing care, and age ≥ 16 years.
For more information, please contact Maureen Gartner, RN at maureen.gartner@uc.edu or (513) 558-0018.